If you select a wheel size and axle type, along with the desired number of wheel-on-stub-axle sets, you'll get an "Add to Cart" option.
I discovered that to send my order to a U.S. address other than California, it would cost $7088.19 to equip my fleet of 104 Athearn diesels with Proto87 wheels.
I'd guess that the main track modifications required for operation would be to turnouts, and specifically to the frogs and guard rail flangeways. Of course, a Proto87 train running on Atlas or even Micro Engineering track might just not cut it. I've read that Central Valley tie strips have better detail (I'm using them on parts of the second level of my layout, but no attempt at Proto87 standards there - they were simply cheaper than flex track).
Anybody can cherry-pick the degree to which they wish to embrace Proto standards, but wheels will likely force you to also upgrade your track to similar standards - otherwise, operations will probably prove frustrating. Beyond that, how far are you willing to go with rolling stock and locomotive detailing, structure upgrading, and scenery, etc., etc.?
Were I just starting out in model railroading but somehow equipped with all I've learned about it in more than 55 years of hands-on experience, I might opt for a full-bore Proto87 experience, but it wouldn't include a locomotive roster of more than two dozen locomotives or over 500 pieces of rolling stock, nor would it involve several hundred feet of track and an ambitious operating plan.
I can see one or two locos, maybe 3 dozen freight cars and a few other interesting pieces of rolling stock, enough structures to support some kind of operation, and all of it set on a layout with burn-your-retinas scenery. Sounds like a lifetime project to me, and I don't have that kind of time left.
Wayne